Jorge el Curioso

Will Ferrell Ted (Man with the Yellow Hat) (voice)

Drew Barrymore Maggie (voice)

David Cross Junior (voice)

Eugene Levy Clovis (voice)

Joan Plowright Ms. Plushbottom (voice)

Dick Van Dyke Mr. Bloomsberry (voice)

Frank Welker George (voice)

Ed O'Ross Ivan (voice)

Michael Chinyamurindi Edu (voice)

Michael Sorich "Seen It" Cab Driver (voice)

Billy West Manager (voice)

Jeff Bennett Salesman (voice)

Kath Soucie Animal Control Receptionist (voice)

Clint Howard Balloon Man (voice)

Shane Baumel Kid (voice)

Timyra-Joi Beatty Kid (voice)

Christopher Chen Kid (voice)

Michaela Jill Murphy Kid (voice)

Alexander Gould Kid (voice)

Terrence Hardy Jr. Kid (voice)